Possible regulatory mechanisms in the ovarian disorders.

Long-term investigation of prevalence of antiovarian antibodies in serum of girls and adolescent women confirm their significantly higher incidence in patients with primary amenorhea (PA), oligomenorhea and secondary amenorhea (OSA). Simultaneously, in association with ovarian disorders, significantly increased levels of gonadotropins, particularly FSH, LH and their ratio (FSH/LH) declare an actual state of the ovary. Because of the result of above-mentioned diseases is a substantial depletion of follicular apparatus; the aim of this study was to analyze morphological and functional design of the human ovary.